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Emanuela Scavo Ph. Understanding the normal cellular hierarchy within the thyroid tissue and the driven-mutations are important prerequisite to identify the cell of origin and the molecular events able to kick-start the tumor. Student: Adipose stem cells in lipofilling procedure and tumoral relapse after surgical treatment Cellular and Molecular Oncology Laboratory Lab Head: Stassi Giorgio Thesis Advisor: Stassi Giorgio The project aim is to value through the coculture system, both in vitro and in vivo, the correlation between BCSCs and adipose tissue and to explore if the potential risk of local dormant tumor cells being stimulated to recurrence after lipofilling.
Legal and moral aspects of human embryonic stem cell research
Project: Carboxyamidotriazole-orotate inhibits the growth of Imatinib-resistant chronic myeloid leukemia cells and modulates exosomes-stimulated angiogenesis Laboratory of Cellular and Molecular Biology, Human Genetics and Proteomic Lab Head: Riccardo Alessandro Thesis Advisor: Riccardo Alessandro The aim of my research project is to test the effect of carboxyamidotriazole-orotate on in vitro and in vivo models of chronic myelogenous leukaemia resistant to the conventional therapy with imatinib mesylate mail: stefania.
We will study their role as possible target for immunotherapy capable to maintain clinical remission for long time. Project: p63 confers the metastatic potential to breast cancer stem cells Laboratory of Cellular and Molecular Pathophysiology Lab Head: Giorgio Stassi Thesis Advisor: Matilde Todaro In vitro and in vivo studies of the expression of different isoforms of p63 and their effect on breast cancer progression, using the breast cancer stem cells as a predictive model.
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Project: Characterization of human tumor-infiltrating effector and regulatory T lymphocytes Laboratory of Infection and Tumor Immunology Lab Head: Francesco Dieli Thesis Advisor: Serena Meraviglia An elevated number of Treg cells can migrate into tumors and suppress effective immuno responses in the tumor microenvironment contributing to the growth of cancers. The aim of my research project is to provide a comprehensive characterization of Tregs, effector T and NK cells, and of mechanisms that control production and function of these cell subsets in different types of cancer.
The modulation of the mechanism underlying Treg induction and suppressor activity may support the development of new immunotherapeutic strategies. Subscribe to this fee journal for more curated articles on this topic.
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Environment for Innovation eJournal. Stem Cell eJournal.
An Ethical Debate on Embryonic Stem Cell Research: Human Dignity or Research Freedom?
Stem cells: Therapy, controversy, and research
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Abstract Present thesis concerns one of the controversial topics of this era - the embryonic stem cell debate, more precisely in connection with their patents, ethics and human rights. Register to save articles to your library Register. Paper statistics. Related eJournals Ethics eJournal Follow.
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